Lion's Mane Fruiting Body Modulates Gut Microbiome

Lion's Mane mushroom has long been known to have a beneficial effect on the gut microbiome. A brand new study showed one new mechanism of that, and that is an immune modulating molecule called Alpha Glucan. All mushrooms contain beta glucans, which support immune health, but alpha glucans are less well known. In this study, alpha glucans in Lion's Mane fruiting body increased beneficial bacteria including lactobacillus and bifidus strains, while inhibiting the harmful bacteria called fusobacterium.

Preparation, Structural Characterization, and In Vitro Modulation of the Gut Microbiota Activity of a Novel α-Glucan in Hericium erinaceus - PubMed